Struggling to fall asleep or stay asleep? You’re not alone. Around one in three UK adults experience insomnia symptoms every week, according to the NHS. For many, Zopiclone offers fast, reliable short-term relief when lifestyle changes alone aren’t enough.
This comprehensive guide covers everything you need to know about Zopiclone in the UK in 2025 – how it works, correct dosage, side effects, safety advice and exactly how to buy Zopiclone online UK legally and safely from a registered pharmacy.
What is Zopiclone and How Does it Work?
Zopiclone is a non-benzodiazepine (“Z-drug”) sleeping tablet that belongs to the cyclopyrrolone class. It is one of the most commonly prescribed medications for short-term insomnia in the UK.
It works by enhancing the activity of GABA (gamma-aminobutyric acid), a neurotransmitter that calms brain activity. The result? You fall asleep faster, experience fewer night-time awakenings, and wake feeling more refreshed — without the heavy “hangover” effect some older sleeping pills cause.
Zopiclone is available in two strengths in the UK:
- Zopiclone 7.5mg (standard adult dose)
- Zopiclone 3.75mg (recommended for over-65s and those sensitive to medicines)
Who is Zopiclone Suitable For?
Zopiclone is licensed for the short-term treatment of severe insomnia that is disabling or causing extreme distress.
It is particularly helpful for:
- People with transient insomnia (e.g. due to shift work or jet lag
- Those experiencing short-term sleep problems caused by stress, bereavement or life events
- Patients who have not responded to sleep hygiene advice alone
It is NOT suitable for long-term daily use because tolerance and dependence can develop.
Correct Zopiclone Dosage – UK Guidelines 2025
| Age Group | Recommended Dose | Maximum Duration |
|---|---|---|
| Adults aged 18–64 | 7.5mg taken just before bed | 2–4 weeks maximum |
| Adults 65+ or with liver/kidney issues | Start at 3.75mg | 2 weeks maximum |
Always take Zopiclone immediately before bedtime and ensure you can have 7–8 hours of uninterrupted sleep. Taking it too late risks next-day drowsiness (“carry-over” effect).
Never exceed the prescribed dose and never take a second tablet if you wake during the night.
Common Side Effects of Zopiclone
Most people tolerate Zopiclone well, but side effects can occur:
Most frequent:
- Metallic or bitter after-taste (affects ~20–30% of users)
- Dry mouth
- Daytime drowsiness or dizziness (especially if <7–8 hours sleep)
Less common but important:
- Memory impairment (anterograde amnesia)
- Headache
- Nausea
- Rare paradoxical effects (increased anxiety, agitation, hallucinations)
Serious side effects are uncommon, but stop treatment and contact a doctor immediately if you experience:
- Sleep-walking, sleep-driving or other complex behaviours
- Severe allergic reaction
- Worsening depression or suicidal thoughts
Who Should NOT Take Zopiclone?
Do not use Zopiclone if you have:
- Severe liver disease
- Sleep apnoea syndrome
- Myasthenia gravis
- Severe breathing difficulties
- History of drug or alcohol dependence
- Allergy to zopiclone or eszopiclone
It is not recommended during pregnancy or breastfeeding.
Is Zopiclone Addictive?
Yes — Zopiclone carries a risk of dependence and withdrawal symptoms if used for more than 4 weeks. The MHRA and NICE guidelines state it should only be used for severe insomnia and for the shortest possible duration (usually 2–4 weeks including tapering).
Withdrawal symptoms can include rebound insomnia, anxiety, tremor, sweating and, in rare cases, seizures. Always taper the dose under medical supervision.
How to Use Zopiclone Safely – 10 Expert Tips
- Use only short-term (maximum 4 weeks)
- Never combine with alcohol or opioids – risk of dangerous respiratory depression
- Avoid driving or operating machinery the next morning until you know how it affects you
- Store securely away from children (it looks like a sweet to toddlers)
- Do not stop suddenly – speak to your doctor about tapering
- Tell your doctor about all other medicines (especially antidepressants, antipsychotics, strong painkillers)
- Avoid grapefruit juice (can increase blood levels)
- If you still can’t sleep after 7–14 days, seek review – continuing rarely helps
- Combine with sleep hygiene for best results (see below)
- Use the lowest effective dose
Sleep Hygiene Tips – Reduce Your Need for Sleeping Tablets
Many patients who follow good sleep habits can reduce or stop Zopiclone entirely:
- Keep a regular sleep schedule – even at weekends
- Create a dark, cool, quiet bedroom (ideal temperature 16–18°C)
- Avoid screens 60–90 minutes before bed (blue light suppresses melatonin)
- Limit caffeine after midday
- Exercise daily but not within 3 hours of bedtime
- Avoid heavy meals or alcohol in the evening
- Try relaxation techniques: CBT-i apps (Sleepio, Sleepstation), mindfulness or progressive muscle relaxation
Where to Buy Zopiclone Online UK Legally & Safely in 2025
Zopiclone is a prescription-only medicine (POM) in the UK. It is illegal to sell it without a valid prescription.
Reputable registered online pharmacies like mymedsshop.co.uk offer genuine UK-licensed Zopiclone 7.5mg and 3.75mg tablets after a free online consultation with a qualified prescriber or by uploading your NHS/private prescription.
Why patients choose mymedsshop.co.uk:
- GPhC-registered pharmacy (check registration number on website footer)
- Genuine Imovane/Zimovane branded or UK-licensed generic tablets
- Next-day delivery available across the UK (including Northern Ireland)
- Discreet plain packaging
- Free online consultation & prescription service
- Outstanding Trustpilot reviews from thousands of UK customers
- Full customer support 7 days a week
We never supply Zopiclone without proper medical assessment — your safety is our priority.
Final Thoughts
Zopiclone remains one of the most effective short-term treatments for debilitating insomnia when used correctly under medical supervision. When combined with good sleep hygiene, many people need only a few weeks of treatment before sleeping naturally again.
Ready for better sleep? Visit mymedsshop.co.uk today to complete our quick, free consultation and buy Zopiclone online UK safely and legally with next-day delivery. Our UK-registered pharmacists are here to help you every step of the way.
Always read the patient information leaflet. Never share your medication. If insomnia persists, speak to your GP — there may be an underlying cause that needs investigation.
Sleep well. Live better. mymedsshop.co.uk – Your trusted UK online pharmacy.

